@article{pmid35975642,

title = {Revised Clinical Practice Guidelines of the Korean Pancreatobiliary Association for Acute Pancreatitis},

author = {Sang Hyub Lee and Jung Wan Choe and Young Koog Cheon and Miyoung Choi and Min Kyu Jung and Dong Kee Jang and Jung Hyun Jo and Jae Min Lee and Eui Joo Kim and Sung Yong Han and Young Hoon Choi and Hyung-Il Seo and Dong Ho Lee and Hong Sik Lee},

doi = {10.5009/gnl220108},

issn = {2005-1212},

year  = {2022},

date = {2022-08-01},

urldate = {2022-08-01},

journal = {Gut Liver},

abstract = {Acute pancreatitis can range from a mild, self-limiting disease requiring no more than supportive care, to severe disease with life-threatening complications. With the goal of providing a recommendation framework for clinicians to manage acute pancreatitis, and to contribute to improvements in national health care, the Korean Pancreatobiliary Association (KPBA) established the Korean guidelines for acute pancreatitis management in 2013. However, many challenging issues exist which often lead to differences in clinical practices. In addition, with newly obtained evidence regarding acute pancreatitis, there have been great changes in recent knowledge and information regarding this disorder. Therefore, the KPBA committee underwent an extensive revision of the guidelines. The revised guidelines were developed using the Delphi method, and the main topics of the guidelines include the following: diagnosis, severity assessment, initial treatment, nutritional support, convalescent treatment, and the treatment of local complications and necrotizing pancreatitis. Specific recommendations are presented, along with the evidence levels and recommendation grades.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Shimizu2022709,

title = {Evidence-based clinical practice guidelines for chronic pancreatitis 2021},

author = {Kyoko Shimizu and Tetsuhide Ito and Atsushi Irisawa and Takao Ohtsuka and Hirotaka Ohara and Atsushi Kanno and Mitsuhiro Kida and Junichi Sakagami and Naohiro Sata and Yoshifumi Takeyama and Junko Tahara and Morihisa Hirota and Nao Fujimori and Atsushi Masamune and Satoshi Mochida and Nobuyuki Enomoto and Tooru Shimosegawa and Kazuhiko Koike},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85136547609&doi=10.1007%2fs00535-022-01911-6&partnerID=40&md5=3bd223fa4dad73fb295975764c146908},

doi = {10.1007/s00535-022-01911-6},

issn = {09441174},

year  = {2022},

date = {2022-01-01},

urldate = {2022-01-01},

journal = {Journal of Gastroenterology},

volume = {57},

number = {10},

pages = {709 – 724},

publisher = {Springer},

abstract = {Background: Chronic pancreatitis (CP) is defined according to the recently proposed mechanistic definition as a pathological fibro-inflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other risk factors who develop persistent pathological responses to parenchymal injury or stress. Methods: The clinical practice guidelines for CP in Japan were revised in 2021 based on the 2019 Japanese clinical diagnostic criteria for CP, which incorporate the concept of a pathogenic fibro-inflammatory syndrome in the pancreas. In this third edition, clinical questions are reclassified into clinical questions, background questions, and future research questions. Results: Based on analysis of newly accumulated evidence, the strength of evidence and recommendations for each clinical question is described in terms of treatment selection, lifestyle guidance, pain control, treatment of exocrine and endocrine insufficiency, and treatment of complications. A flowchart outlining indications, treatment selection, and policies for cases in which treatment is ineffective is provided. For pain control, pharmacological treatment and the indications and timing for endoscopic and surgical treatment have been updated in the revised edition. Conclusions: These updated guidelines provide clinicians with useful information to assist in the diagnosis and treatment of CP. © 2022, The Author(s).},

note = {Cited by: 0; All Open Access, Green Open Access, Hybrid Gold Open Access},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Takada20221057,

title = {JPN clinical practice guidelines 2021 with easy-to-understand explanations for the management of acute pancreatitis},

author = {Tadahiro Takada and Shuji Isaji and Toshihiko Mayumi and Masahiro Yoshida and Yoshifumi Takeyama and Takao Itoi and Keiji Sano and Yusuke Iizawa and Atsushi Masamune and Morihisa Hirota and Kohji Okamoto and Dai Inoue and Nobuya Kitamura and Yasuhisa Mori and Shuntaro Mukai and Seiki Kiriyama and Kunihiro Shirai and Asuka Tsuchiya and Ryota Higuchi and Teijiro Hirashita},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85129146187&doi=10.1002%2fjhbp.1146&partnerID=40&md5=3ef1620f91bab2c49ba4f7dfc1fa90e9},

doi = {10.1002/jhbp.1146},

issn = {18686974},

year  = {2022},

date = {2022-01-01},

urldate = {2022-01-01},

journal = {Journal of Hepato-Biliary-Pancreatic Sciences},

volume = {29},

number = {10},

pages = {1057 – 1083},

publisher = {John Wiley and Sons Inc},

abstract = {Background: In preparing the Japanese (JPN) guidelines for the management of acute pancreatitis 2021, the committee focused the issues raised by the results of nationwide epidemiological survey in 2016 in Japan. Method: In addition to a systematic search using the previous JPN guidelines, papers published from January 2014 to September 2019 were searched for the contents to be covered by the guidelines based on the concept of GRADE system. Results: Thirty-six clinical questions (CQ) were prepared in 15 subject areas. Based on the facts that patients diagnosed with severe disease by both Japanese prognostic factor score and contrast-enhanced computed tomography (CT) grade had a high fatality rate and that little prognosis improvement after 2 weeks of disease onset was not obtained, we emphasized the importance of Pancreatitis Bundles, which were shown to be effective in improving prognosis, and the CQ sections for local pancreatic complications had been expanded to ensure adoption of a step-up approach. Furthermore, on the facts that enteral nutrition for severe acute pancreatitis was not started early within 48 h of admission and that unnecessary prophylactic antibiotics was used in almost all cases, we emphasized early enteral nutrition in small amounts even if gastric feeding is used and no prophylactic antibiotics are administered in mild pancreatitis. Conclusion: All the members of the committee have put a lot of effort into preparing the extensively revised guidelines in the hope that more people will have a common understanding and that better medical care will be spread. © 2022 Japanese Society of Hepato-Biliary-Pancreatic Surgery.},

note = {Cited by: 5},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Jaber2022,

title = {Guidelines for the management of patients with severe acute pancreatitis, 2021},

author = {Samir Jaber and Marc Garnier and Karim Asehnoune and Fanny Bounes and Louis Buscail and Jean-Baptiste Chevaux and Claire Dahyot-Fizelier and Lucie Darrivere and Matthieu Jabaudon and Olivier Joannes-Boyau and Yoann Launey and Eric Levesque and Philippe Levy and Philippe Montravers and Laurent Muller and Thomas Rimmelé and Claire Roger and Céline Savoye-Collet and Philippe Seguin and Jean-Pierre Tasu and Ronan Thibault and Geoffroy Vanbiervliet and Emmanuel Weiss and Audrey De Jong},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85130554795&doi=10.1016%2fj.accpm.2022.101060&partnerID=40&md5=1e705243013a8598f9f3f165688c3ea4},

doi = {10.1016/j.accpm.2022.101060},

issn = {23525568},

year  = {2022},

date = {2022-01-01},

urldate = {2022-01-01},

journal = {Anaesthesia Critical Care and Pain Medicine},

volume = {41},

number = {3},

publisher = {Elsevier Masson s.r.l.},

abstract = {Objective: To provide guidelines for the management of the intensive care patient with severe acute pancreatitis. Design: A consensus committee of 22 experts was convened. A formal conflict-of-interest (COI) policy was developed at the beginning of the process and enforced throughout. The entire guideline construction process was conducted independently of any industrial funding (i.e. pharmaceutical, medical devices). The authors were required to follow the rules of the Grading of Recommendations Assessment, Development and Evaluation (GRADE®) system to guide assessment of quality of evidence. The potential drawbacks of making strong recommendations in the presence of low-quality evidence were emphasised. Methods: The most recent SFAR and SNFGE guidelines on the management of the patient with severe pancreatitis were published in 2001. The literature now is sufficient for an update. The committee studied 14 questions within 3 fields. Each question was formulated in a PICO (Patients Intervention Comparison Outcome) format and the relevant evidence profiles were produced. The literature review and recommendations were made according to the GRADE® methodology. Results: The experts' synthesis work and their application of the GRADE® method resulted in 24 recommendations. Among the formalised recommendations, 8 have high levels of evidence (GRADE 1+/−) and 12 have moderate levels of evidence (GRADE 2+/−). For 4 recommendations, the GRADE method could not be applied, resulting in expert opinions. Four questions did not find any response in the literature. After one round of scoring, strong agreement was reached for all the recommendations. Conclusions: There was strong agreement among experts for 24 recommendations to improve practices for the management of intensive care patients with severe acute pancreatitis. © 2022},

note = {Cited by: 2; All Open Access, Bronze Open Access, Green Open Access},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Strand2022,

title = {AGA Clinical Practice Update on the Endoscopic Approach to Recurrent Acute and Chronic Pancreatitis: Expert Review},

author = {Daniel S. Strand and Ryan J. Law and Dennis Yang and B. Joseph Elmunzer},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85136313810&doi=10.1053%2fj.gastro.2022.07.079&partnerID=40&md5=c1c3ef7273b7cc0697726a4153ddd448},

doi = {10.1053/j.gastro.2022.07.079},

issn = {00165085},

year  = {2022},

date = {2022-01-01},

urldate = {2022-01-01},

journal = {Gastroenterology},

publisher = {W.B. Saunders},

abstract = {Description: The purpose of this American Gastroenterological Association (AGA) Clinical Practice Update Expert Review is to provide practical, evidence-based guidance to clinicians regarding the role of endoscopy for recurrent acute and chronic pancreatitis. Methods: This expert review was commissioned and approved by the AGA Institute Clinical Practice Updates Committee and the AGA Governing Board to provide guidance on a topic of clinical importance to the AGA membership, underwent internal peer review by the Clinical Practice Updates Committee (CPUC), and external peer review through standard procedures of Gastroenterology. This review is framed around the 8 best practice advice points agreed upon by the authors, based on the results of randomized controlled trials, observational studies, systematic reviews and meta-analyses, as well expert consensus in this field. Best Practice Advice Statements BEST PRACTICE ADVICE 1: After an unrevealing initial evaluation, endoscopic ultrasound is the preferred diagnostic test for unexplained acute and recurrent pancreatitis. Magnetic resonance imaging with contrast and cholangiopancreatography is a reasonable complementary or alternative test to endoscopic ultrasound, based on local expertise and availability. BEST PRACTICE ADVICE 2: The role of endoscopic retrograde cholangiopancreatography (ERCP) for reducing the frequency of acute pancreatitis episodes in patients with pancreas divisum is controversial, but minor papilla endotherapy may be considered, particularly for those with objective signs of outflow obstruction, such as a dilated dorsal pancreatic duct and/or santorinicele. There is no role for ERCP to treat pain alone in patients with pancreas divisum. BEST PRACTICE ADVICE 3: The role of ERCP for reducing the frequency of pancreatitis episodes in patients with unexplained recurrent acute pancreatitis and standard pancreatic ductal anatomy is controversial and should only be considered after a comprehensive discussion of the uncertain benefits and potentially severe procedure-related adverse events. When pursued, ERCP with biliary sphincterotomy alone may be preferable to dual sphincterotomy. BEST PRACTICE ADVICE 4: Surgical intervention should be considered over endoscopic therapy for long-term treatment of patients with painful obstructive chronic pancreatitis. Endoscopic intervention is a reasonable alternative to surgery for suboptimal operative candidates or those who favor a less invasive approach, assuming they are clearly informed that the best practice advice primarily favors surgery. BEST PRACTICE ADVICE 5: When ERCP is pursued, small (≤5mm) main pancreatic duct stones can be treated with pancreatography and conventional stone extraction maneuvers. For larger stones, extracorporeal shockwave lithotripsy and/or pancreatoscopy with intraductal lithotripsy may be required. BEST PRACTICE ADVICE 6: When ERCP is pursued, prolonged stent therapy (6–12 months) is effective for treating symptoms and remodeling main pancreatic duct strictures. The preferred approach is to place and sequentially add multiple plastic stents in parallel (upsizing); emerging evidence suggests that fully covered self-expanding metal stents may have a role for this indication, but additional research is necessary. BEST PRACTICE ADVICE 7: ERCP with stent insertion is the preferred treatment for benign biliary stricture due to chronic pancreatitis. FCSEMS placement is favored over multiple plastic stents whenever feasible, given similar efficacy but significantly reduced need for stent exchange procedures during the treatment course. BEST PRACTICE ADVICE 8: Celiac plexus block should not be routinely performed for the management of pain due to chronic pancreatitis. The decision to proceed with celiac plexus block in selected patients with debilitating pain in whom other therapeutic measures have failed can be considered on a case-by-case basis, but only after discussion of the unclear outcomes of this intervention and its procedural risks. © 2022 AGA Institute},

note = {Cited by: 0; All Open Access, Bronze Open Access},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Laterre2022,

title = {Improving the management of severe acute pancreatitis: The new guidelines from the French Society of Anaesthesia and Intensive Care Medicine},

author = {Pierre-François Laterre and Christine Collienne},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85132330222&doi=10.1016%2fj.accpm.2022.101103&partnerID=40&md5=0aca8b84e86a40603ac72e75f87e9967},

doi = {10.1016/j.accpm.2022.101103},

issn = {23525568},

year  = {2022},

date = {2022-01-01},

urldate = {2022-01-01},

journal = {Anaesthesia Critical Care and Pain Medicine},

volume = {41},

number = {3},

publisher = {Elsevier Masson s.r.l.},

note = {Cited by: 0},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Linee guida sulla pancreatite acuta e cronica},

author = {Antonino Cartabellotta and Silvia Tedesco and Giovanni Pomponio},

url = {https://www.evidence.it/lettura_pdf.php?id_articolo=545},

year  = {2019},

date = {2019-01-15},

journal = {Evidence},

volume = {11},

issue = {11},

pages = {e1000193},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Leppäniemi2019,

title = {2019 WSES guidelines for the management of severe acute pancreatitis},

author = {Ari Leppäniemi and Matti Tolonen and Antonio Tarasconi and Helmut Segovia-Lohse and Emiliano Gamberini and Andrew W. Kirkpatrick and Chad G. Ball and Neil Parry and Massimo Sartelli and Daan Wolbrink and Harry Van Goor and Gianluca Baiocchi and Luca Ansaloni and Walter Biffl and Federico Coccolini and Salomone Di Saverio and Yoram Kluger and Ernest Moore and Fausto Catena},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85067284984&doi=10.1186%2fs13017-019-0247-0&partnerID=40&md5=25f5f4e96b4c4893442bd204fdc56052},

doi = {10.1186/s13017-019-0247-0},

issn = {17497922},

year  = {2019},

date = {2019-01-01},

urldate = {2019-01-01},

journal = {World Journal of Emergency Surgery},

volume = {14},

number = {1},

publisher = {BioMed Central Ltd.},

abstract = {Although most patients with acute pancreatitis have the mild form of the disease, about 20-30% develops a severe form, often associated with single or multiple organ dysfunction requiring intensive care. Identifying the severe form early is one of the major challenges in managing severe acute pancreatitis. Infection of the pancreatic and peripancreatic necrosis occurs in about 20-40% of patients with severe acute pancreatitis, and is associated with worsening organ dysfunctions. While most patients with sterile necrosis can be managed nonoperatively, patients with infected necrosis usually require an intervention that can be percutaneous, endoscopic, or open surgical. These guidelines present evidence-based international consensus statements on the management of severe acute pancreatitis from collaboration of a panel of experts meeting during the World Congress of Emergency Surgery in June 27-30, 2018 in Bertinoro, Italy. The main topics of these guidelines fall under the following topics: Diagnosis, Antibiotic treatment, Management in the Intensive Care Unit, Surgical and operative management, and Open abdomen. © 2019 The Author(s).},

note = {Cited by: 210; All Open Access, Gold Open Access, Green Open Access},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Goodchild2019292,

title = {Practical guide to the management of acute pancreatitis},

author = {George Goodchild and Manil Chouhan and Gavin J. Johnson},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85062339295&doi=10.1136%2fflgastro-2018-101102&partnerID=40&md5=e1afc25a5c81c9d6d18852deab43aea5},

doi = {10.1136/flgastro-2018-101102},

issn = {20414137},

year  = {2019},

date = {2019-01-01},

urldate = {2019-01-01},

journal = {Frontline Gastroenterology},

volume = {10},

number = {3},

pages = {292 – 299},

publisher = {BMJ Publishing Group},

abstract = {Acute pancreatitis (AP) is characterised by inflammation of the exocrine pancreas and is associated with acinar cell injury and both a local and systemic inflammatory response. AP may range in severity from self-limiting, characterised by mild pancreatic oedema, to severe systemic inflammation with pancreatic necrosis, organ failure and death. Several international guidelines have been developed including those from the joint International Association of Pancreatology and American Pancreatic Association, American College of Gastroenterology and British Society of Gastroenterology. Here we discuss current diagnostic and management challenges and address the common dilemmas in AP. © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.},

note = {Cited by: 22; All Open Access, Bronze Open Access, Green Open Access},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Crockett20181096,

title = {American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis},

author = {Seth D. Crockett and Sachin Wani and Timothy B. Gardner and Yngve Falck-Ytter and Alan N. Barkun and Joseph Feuerstein and Steven Flamm and Ziad Gellad and Lauren Gerson and Samir Gupta and Ikuo Hirano and John Inadomi and Geoffrey C. Nguyen and Joel H. Rubenstein and Siddharth Singh and Walter E. Smalley and Neil Stollman and Sarah Street and Shahnaz Sultan and Santhi S. Vege and Sachin B. Wani and David Weinberg},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043233164&doi=10.1053%2fj.gastro.2018.01.032&partnerID=40&md5=b3f7f63d5a96379d3bb63b978be7d8e6},

doi = {10.1053/j.gastro.2018.01.032},

issn = {00165085},

year  = {2018},

date = {2018-01-01},

urldate = {2018-01-01},

journal = {Gastroenterology},

volume = {154},

number = {4},

pages = {1096 – 1101},

publisher = {W.B. Saunders},

note = {Cited by: 318; All Open Access, Bronze Open Access},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Greenberg2016128,

title = {Clinical practice guideline: Management of acute pancreatitis},

author = {Joshua A. Greenberg and Jonathan Hsu and Mohammad Bawazeer and John Marshall and Jan O. Friedrich and Avery Nathens and Natalie Coburn and Gary R. May and Emily Pearsall and Robin S. McLeod},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84962431668&doi=10.1503%2fcjs.015015&partnerID=40&md5=2db89921f7f0f0ff44205f31a11157d4},

doi = {10.1503/cjs.015015},

issn = {0008428X},

year  = {2016},

date = {2016-01-01},

urldate = {2016-01-01},

journal = {Canadian Journal of Surgery},

volume = {59},

number = {2},

pages = {128 – 140},

publisher = {Canadian Medical Association},

abstract = {There has been an increase in the incidence of acute pancreatitis reported worldwide. Despite improvements in access to care, imaging and interventional techniques, acute pancreatitis continues to be associated with significant morbidity and mortality. Despite the availability of clinical practice guidelines for the management of acute pancreatitis, recent studies auditing the clinical management of the condition have shown important areas of noncompliance with evidence-based recommendations. This underscores the importance of creating understandable and implementable recommendations for the diagnosis and management of acute pancreatitis. The purpose of the present guideline is to provide evidence-based recommendations for the management of both mild and severe acute pancreatitis as well as the management of complications of acute pancreatitis and of gall stone-induced pancreatitis. © 2016 8872147 Canada Inc.},

note = {Cited by: 169; All Open Access, Green Open Access},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Pezzilli2015532,

title = {Consensus guidelines on severe acute pancreatitis},

author = {Raffaele Pezzilli and Alessandro Zerbi and Donata Campra and Gabriele Capurso and Rita Golfieri and Paolo G. Arcidiacono and Paola Billi and Giovanni Butturini and Lucia Calculli and Renato Cannizzaro and Silvia Carrara and Stefano Crippa and Raffaele De Gaudio and Paolo De Rai and Luca Frulloni and Ernesto Mazza and Massimiliano Mutignani and Nico Pagano and Piergiorgio Rabitti and Gianpaolo Balzano},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84937636431&doi=10.1016%2fj.dld.2015.03.022&partnerID=40&md5=2d26e6c79983865132915649d474df3a},

doi = {10.1016/j.dld.2015.03.022},

issn = {15908658},

year  = {2015},

date = {2015-01-01},

urldate = {2015-01-01},

journal = {Digestive and Liver Disease},

volume = {47},

number = {7},

pages = {532 – 543},

publisher = {Elsevier},

abstract = {This Position Paper contains clinically oriented guidelines by the Italian Association for the Study of the Pancreas (AISP) for the diagnosis and treatment of severe acute pancreatitis. The statements were formulated by three working groups of experts who searched and analysed the most recent literature; a consensus process was then performed using a modified Delphi procedure. The statements provide recommendations on the most appropriate definition of the complications of severe acute pancreatitis, the diagnostic approach and the timing of conservative as well as interventional endoscopic, radiological and surgical treatments. © 2015 Editrice Gastroenterologica Italiana S.r.l.},

note = {Cited by: 96},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Yokoe2015405,

title = {Japanese guidelines for the management of acute pancreatitis: Japanese Guidelines 2015},

author = {Masamichi Yokoe and Tadahiro Takada and Toshihiko Mayumi and Masahiro Yoshida and Shuji Isaji and Keita Wada and Takao Itoi and Naohiro Sata and Toshifumi Gabata and Hisato Igarashi and Keisho Kataoka and Masahiko Hirota and Masumi Kadoya and Nobuya Kitamura and Yasutoshi Kimura and Seiki Kiriyama and Kunihiro Shirai and Takayuki Hattori and Kazunori Takeda and Yoshifumi Takeyama and Morihisa Hirota and Miho Sekimoto and Satoru Shikata and Shinju Arata and Koichi Hirata},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84929920268&doi=10.1002%2fjhbp.259&partnerID=40&md5=cc758dd45e1d0a9ccbcdd19c00f34e16},

doi = {10.1002/jhbp.259},

issn = {18686974},

year  = {2015},

date = {2015-01-01},

urldate = {2015-01-01},

journal = {Journal of Hepato-Biliary-Pancreatic Sciences},

volume = {22},

number = {6},

pages = {405 – 432},

publisher = {Blackwell Publishing Asia},

abstract = {Background Japanese (JPN) guidelines for the management of acute pancreatitis were published in 2006. The severity assessment criteria for acute pancreatitis were later revised by the Japanese Ministry of Health, Labour and Welfare (MHLW) in 2008, leading to their publication as the JPN Guidelines 2010. Following the 2012 revision of the Atlanta Classifications of Acute Pancreatitis, in which the classifications of regional complications of pancreatitis were revised, the development of a minimally invasive method for local complications of pancreatitis spread, and emerging evidence was gathered and revised into the JPN Guidelines. Methods A comprehensive evaluation was carried out on the evidence for epidemiology, diagnosis, severity, treatment, post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis and clinical indicators, based on the concepts of the GRADE system (Grading of Recommendations Assessment, Development and Evaluation). With the graded recommendations, where the evidence was unclear, Meta-Analysis team for JPN Guidelines 2015 conducted an additional new meta-analysis, the results of which were included in the guidelines. Results Thirty-nine questions were prepared in 17 subject areas, for which 43 recommendations were made. The 17 subject areas were: Diagnosis, Diagnostic imaging, Etiology, Severity assessment, Transfer indication, Fluid therapy, Nasogastric tube, Pain control, Antibiotics prophylaxis, Protease inhibitor, Nutritional support, Intensive care, management of Biliary Pancreatitis, management of Abdominal Compartment Syndrome, Interventions for the local complications, Post-ERCP pancreatitis and Clinical Indicator (Pancreatitis Bundles 2015). Meta-analysis was conducted in the following four subject areas based on randomized controlled trials: (1) prophylactic antibiotics use; (2) prophylactic pancreatic stent placement for the prevention of post-ERCP pancreatitis; (3) prophylactic non-steroidal anti-inflammatory drugs (NSAIDs) for the prevention of post-ERCP pancreatitis; and (4) peritoneal lavage. Using the results of the meta-analysis, recommendations were graded to create useful information. In addition, a mobile application was developed, which made it possible to diagnose, assess severity and check pancreatitis bundles. Conclusions The JPN Guidelines 2015 were prepared using the most up-to-date methods, and including the latest recommended medical treatments, and we are confident that this will make them easy for many clinicians to use, and will provide a useful tool in the decision-making process for the treatment of patients, and optimal medical support. The free mobile application and calculator for the JPN Guidelines 2015 is available via http://www.jshbps.jp/en/guideline/jpn-guideline2015.html © 2015 Japanese Society of Hepato-Biliary-Pancreatic Surgery.},

note = {Cited by: 241},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lankisch201585,

title = {Acute pancreatitis},

author = {Paul Georg Lankisch and Minoti Apte and Peter A Banks},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84937516207&doi=10.1016%2fS0140-6736%2814%2960649-8&partnerID=40&md5=e7aba6b1e13339fe3c102676d0a330cd},

doi = {10.1016/S0140-6736(14)60649-8},

issn = {01406736},

year  = {2015},

date = {2015-01-01},

urldate = {2015-01-01},

journal = {The Lancet},

volume = {386},

number = {9988},

pages = {85 – 96},

publisher = {Lancet Publishing Group},

abstract = {Acute pancreatitis, an inflammatory disorder of the pancreas, is the leading cause of admission to hospital for gastrointestinal disorders in the USA and many other countries. Gallstones and alcohol misuse are long-established risk factors, but several new causes have emerged that, together with new aspects of pathophysiology, improve understanding of the disorder. As incidence (and admission rates) of acute pancreatitis increase, so does the demand for effective management. We review how to manage patients with acute pancreatitis, paying attention to diagnosis, differential diagnosis, complications, prognostic factors, treatment, and prevention of second attacks, and the possible transition from acute to chronic pancreatitis. © 2015 Elsevier Ltd.},

note = {Cited by: 615},

keywords = {},

pubstate = {published},

tppubtype = {article}

}