Principali per le Malattie del Fegato

Abbiamo raccolto in questa pagina le principali linee guida nazionale ed internazionali sulle principali malattie del fegato, principalmente quelle di interesse chirurgico.

Scorrendo in basso potrai trovare i documenti che riguardano:

      • Epatocarcinoma
      • Colangiocarcinoma
      • Metastasi epatiche
      • Tumore della Colecisti
      • Lesioni focali epatiche
      • Tumori benigni del Fegato
      • Resezioni epatiche laparoscopiche 
      • Trapianto di Fegato
      • Calcolosi biliare
      • Alterazioni degli indici di laboratorio della funzionalità epatica

Epatocarcinoma

Linee guida redatte dalle principali Società Scietifiche Italiane che si occupano del trattamento dell’epatocarcinoma

Raccomandazioni Multisocietarie Italiane
(AISF, AIOM, IT‐IHPBA, SIC, SIRM, SITO) per la gestione integrata del paziente con Epatocarcinoma

Linee Guida EASL (European Association for the Study of the Liver) pubblicate nel 2018

European Association for the Study of the Liver.
EASL Clinical Practice Guidelines: Management of Hepatocellular Carcinoma
J Hepatol. 2018 Jul;69(1):182-236

Linea Guida AASLD (American Association for the Study of Liver Diseases) pubblicate nel 2018  (in lingua inglese)

Marrero JA, Kulik LM, Sirlin CB, et al. Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology. 2018;68(2):723‐750

Linea Guida AASLD (American Association for the Study of Liver Diseases) pubblicate nel 2018  (in lingua inglese)

Marrero JA, Kulik LM, Sirlin CB, et al. Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology. 2018;68(2):723‐750

Colangiocarcinoma

Alvaro D, Cannizzaro R, Labianca R, Valvo F, Farinati F
Cholangiocarcinoma: A position paper by the Italian Society of Gastroenterology (SIGE), the Italian Association of Hospital Gastroenterology (AIGO), the Italian Association of Medical Oncology (AIOM) and the Italian Association of Oncological Radiotherapy (AIRO)
Dig Liver Dis. 2010 Dec;42(12):831-8.

Bridgewater J, Galle PR, Khan SA, Llovet JM, Park JW, Patel T, Pawlik TM, Gores GJ
Guidelines for the Diagnosis and Management of Intrahepatic Cholangiocarcinoma.
J Hepatol. 2014 Jun;60(6):1268-89

Mansour JC, Aloia TA, Crane CH, Heimbach JK, Nagino M, Vauthey JN.
Hilar Cholangiocarcinoma: Expert Consensus Statement
HPB (Oxford). 2015 Aug;17(8):691-9.

Weber SM, Ribero D, O’Reilly EM, Kokudo N, Miyazaki M, Pawlik TM.
Intrahepatic Cholangiocarcinoma: Expert Consensus Statement
HPB (Oxford). 2015 Aug;17(8):669-80.

Metastasi Epatiche

Lorem

Garden OJ, Rees M, Poston GJ, Mirza D, Saunders M, Ledermann J, Primrose JN, Parks RW
Guidelines for resection of colorectal cancer liver metastases
Gut 2006;55;iii1-iii8

Van Cutsem E, Cervantes A, Nordlinger B, Arnold D, on behalf of the ESMO Guidelines Working Group
Metastatic colorectal cancer: ESMO Clinical Practice – Guidelines for diagnosis, treatment and follow-up
Annals of Oncology 00 (0): iii1–iii9, 2014

Salvatore L, Aprile G, Arnoldi E, Aschele C, Carnaghi C, Cosimelli M, Maiello E, Normanno N, Sciallero S, Valvo F, Beretta GD
Management of metastatic colorectal cancer patients: guidelines of the Italian Medical Oncology Association (AIOM)
ESMO Open 2017;2:e000147

Van Cutsem E, Cervantes A, Adam R, Sobrero A, Van Krieken JH, Aderka D, Aranda Aguilar E, Bardelli A, Benson A, Bodoky G, Ciardiello F, D’Hoore A, Diaz-Rubio E, Douillard JY, Ducreux M, Falcone A, Grothey A, Gruenberger T, Haustermans K, Heinemann V, Hoff P, Köhne CH, Labianca R, Laurent-Puig P, Ma B, Maughan T, Muro K, Normanno N, Österlund P, Oyen WJG, Papamichael D, Pentheroudakis G, Pfeiffer P, Price TJ, Punt C, Ricke J, Roth A, Salazar R, Scheithauer W, Schmoll HJ, Tabernero J, Taïeb J, Tejpar S, Wasan H, Yoshino T, Zaanan A, Arnold D
ESMO consensus guidelines for the management of patients with metastatic colorectal cancer.
Annals of Oncology 27: 1386–1422, 2016

Yoshino T, Arnold D, Taniguchi H, Pentheroudakis G, Yamazaki K, Xu RH, Kim TW, Ismail F, Tan IB, Yeh KH, Grothey A, Zhang S, Ahn JB, Mastura MY, Chong D, Chen LT, Kopetz S, Eguchi-Nakajima T, Ebi H, Ohtsu A, Cervantes A, Muro K, Tabernero J, Minami H, Ciardiello F, Douillard JY
Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer: a JSMO–ESMO initiative endorsed by CSCO, KACO, MOS, SSO and TOS
Annals of Oncology 29: 44–70, 2018

Tumore della Colecisti

Aloia TA, Jarufe N, Javle M, Maithel SK, Roa JC, Adsay V, Coimbra FJF, Jarnagin WR
Gallbladder Cancer: expert consensus statement
HPB 2015, 17, 681–690

Han HS, Yoon YS, Agarwal AK, Belli G, Itano O, Gumbs AA, Yoon DS, Kang CM, Lee SE, Wakai T, Troisi RI
Laparoscopic Surgery for Gallbladder Cancer: An Expert Consensus Statement
Dig Surg. 2019;36(1):1-6

Lesioni focali epatiche

Linee guida pubblicate dall’American Journal of Gastroenterology sulla definizione dei noduli del fegato (documento in lingua inglese, scaricabile direttamente dal sito).

Marrero JA, Ahn J, Rajender Reddy K; Americal College of Gastroenterology. ACG clinical guideline: the diagnosis and management of focal liver lesions. Am J Gastroenterol. 2014;109(9):1328‐1348.

Tumori Benigni del Fegato

Linee Guida sulla Gestione dei Tumori Benigni del fegato, pubblicate dall’EASL (European Association for the Study of Liver Deaseases) nel 2016 (in lingua inglese).

 

European Association for the Study of the Liver (EASL)
EASL Clinical Practice Guidelines on the Management of Benign Liver Tumours
J Hepatol. 2016 Aug;65(2):386-98

Resezioni Epatiche Laparoscopiche

Buell JF, Cherqui D, Geller DA
The International Position on Laparoscopic Liver Surgery: The Louisville Statement, 2008
Ann Surg. 2009;250:825–830

Wakabayashi G, Cherqui D, Geller DA, et al
Recommendations for laparoscopic liver resection: a report from the second International Consensus Conference held in Morioka
Ann Surgery. 2015;261:619–629.

Abu Hilal M, Aldrighetti L, Dagher I, Edwin B, Troisi RI, Alikhanov R, Aroori S, Belli G, Besselink M, Briceno J, Gayet B, D’Hondt M, Lesurtel M, Menon K, Lodge P, Rotellar F, Santoyo J, Scatton O, Soubrane O, Sutcliffe R, Van Dam R, White S, Halls MC, Cipriani F, Van der Poel M, Ciria R, Barkhatov L, Gomez-Luque Y, Ocana-Garcia S, Cook A, Buell J, Clavien PA, Dervenis C, Fusai G, Geller D, Lang H, Primrose J, Taylor M, Van Gulik T, Wakabayashi G, Asbun H, Cherqui D.
The Southampton Consensus Guidelines for Laparoscopic Liver Surgery: From Indication to Implementation.
Ann Surg. 2018 Jul;268(1):11-18

Trapianto di Fegato

Linea guida dell’Associazione Americana per lo Studio delle Malattie del Fegato (AASLD) per l’inserimento dei pazienti adulti nella lista di attesa per il trapianto di fegato, pubblicate nel 2014 (in lingua inglese)

Martin P, DiMartini A, Feng S, Brown R Jr, Fallon M. Evaluation for liver transplantation in adults: 2013 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation. Hepatology. 2014;59(3):1144‐1165

Pubblicazione scientifica redatta dai Centri italiani di trapianto di fegato sulla allocazione degli organi.

Cillo U, Burra P, Mazzaferro V, Belli L, Pinna AD, Spada M, Nanni Costa A, Toniutto P; I-BELT (Italian Board of Experts in the Field of Liver Transplantation).
A Multistep, Consensus-Based Approach to Organ Allocation in Liver Transplantation: Toward a “Blended Principle Model”.
Am J Transplant. 2015 Oct;15(10):2552-61

Linee guida dell’Associazione Europea per lo Studio del Fegato (EASL) sul Trapianto di fegato (in lingua inglese)

European Association for the Study of the Liver.
EASL Clinical Practice Guidelines: Liver transplantation.
J Hepatol. 2016 Feb;64(2):433-485

Calcolosi biliare

Linee Guida sulla prevenzione, la diagnosi ed il trattamento della calcolosi biliare pubblicate dall’EASL (European Association for the Study of the Liver) nel 2016 (in lingua inglese)

European Association for the Study of the Liver (EASL)
EASL Clinical Practice Guidelines on the prevention, diagnosis and treatment of gallstones. 
J Hepatol. 2016 Jul;65(1):146-181

Alterazioni negli esami di laboratorio del Fegato

Linee guida pubblicate dall’American Journal of Gastroenterology sull’interpretazione degli esami di laboratorio della funzione epatica che risultano alterati (in lingua inglese, scaricabili direttamente dal sito).

Kwo PY, Stanley C, Joseph KL
ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries
Am J Gastroenterol: 2017, 112(1): 18-35